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Condition(s) targeted: Cough Intervention: IR Tablet under Fasted conditions (Drug); ER Tablet under Fed Conditions (Drug); ER Tablet under Fasted Conditions (Drug) Phase: Phase 1 Status: Completed Sponsored by: Nexgen Pharma, Inc The objectives of this study are (a) to determine if drug levels from a single dose of an extended-release Codeine/Guaifenesin tablet are similar to an immediate-release tablet given every four hours containing lower doses considered safe for over-the-counter use; (b) to evaluate if food affects the drug levels of this extended-release Codeine/Guaifenesin tablet after a single administration; and (c) to assess the safety and tolerability of the Codeine/Guaifenesin extended-release and immediate release tablet formulations.

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Expectorant is an agent that promotes the ejection of pegm, mucus or other material from the throat, bronchi, trachea or lungs.

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The primary objective of this study was to compare the bioavailability of paracetamol, phenylephrine hydrocoride and guaifenesin in a new oral syrup with an established oral reference product.

Clinical trial Single Dose Trial of Extended Release

Guaifenesin dosage is generally raised 300 mgs a day at a time . free, because many symptoms may be due to other processes, but you will . Guaifenesin dosage is generally raised 300 mgs a day at a time .


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