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Amlodipine Generic for Norvasc Side Effects, Dosage &

Treatment of chronic stable angina and vasospastic angina (Prinzmetal or variant angina) and angiographiy documented coronary artery disease (CAD) in patients without heart failure or ejection fraction (EF) Headache (7.3%) Fatue (4.5%) Palpitations (0.7-4.5%) Dizziness (1.1-3.4%) Nausea (2.9%) Flushing (0.7-2.6%) Abdominal pain (1.6%) Somnolence (1.4%) Male sexual disorder (1-2%) Drowsiness (1%) Pruritus (1-2%) Skin rash (1-2%) Muscle cramps (1-2%) Muscle weakness (1-2%) Congestive heart failure (CHF) Persistent progressive dermatologic reactions Symptomatic hypotension with or without syncope possible, particularly with severe aortic stenosis; because of gradual onset of action, acute hypotension unlikely Worsening of angina and acute myocardial infarction (MI) can develop after dose is started or increased, particularly with severe obstructive CAD Peripheral edema may develop within 2-3 weeks of starting therapy Use with caution in patients with hypertrophic cardiomyopathy; reduction in afterload may worsen symptoms associated with this condition May reduce coronary perfusion and result in ischemia in patients with severe aortic stenosis; use caution Extensively metabolized by liver; titrate dose slowly with severe hepatic impairment Initiate at lower dose in the elderly Titrate dose every 7-14 days on a given dose; peak antihypertensive effect is delayed Co-administration with CYP3A inhibitors (moderate and strong) results in increased systemic exposure to amlodipine and may require dose reduction; monitor for symptoms of hypotension and edema when amlodipine is co-administered with CYP3A inhibitors to determine the need for dose adjustment Amlodipine may increase systemic exposure of cyclosporine or tacrolimus when co-administered; frequent monitoring of trough blood levels of cyclosporine and tacrolimus recommended; adjust dose when appropriate Inhibits transmembrane influx of extracellular calcium ions across membranes of myocardial cells and vascular smooth muscle cells without changing serum calcium concentrations; this inhibits cardiac and vascular smooth muscle contraction, thereby dilating main coronary and systemic arteries Increases myocardial oxygen delivery in patients with vasospastic angina The above information is provided for general informational and educational purposes only.

Amlodipine Besylate Norvasc - Pet, Dog and Cat Medication and.

If you are sensitive to or have ever had an allergic reaction to Norvasc, do not start or stop taking your other medicines including any other blood pressure medicines, without talking to your doctor if you experience headache, insomnia, nausea, diarrhea, or constipation. Continue to take Amlodipine and talk to your doctor if you experience serious side effects, stop taking Norvasc, as a slow reduction in the dose may be needed.

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Amlodipine Besylate is used to treat hypertension (hh blood pressure), especially in cats with kidney disease.

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Amlodipine Besylate should be given according to your veterinarian’s instructions.

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